H42®: the collagen hydrogel that redefines the treatment of periodontal and peri-implant pockets
H42® is a collagen-based hydrogel designed to provide effective sealing and a biologically favourable environment following mechanical treatment of periodontal and peri-implant pockets. Its advanced formulation combines purified equine collagen, resorbable polymers, and ascorbic acid with visco-modulatory function, providing stable consistency, controlled adhesion, and excellent adaptability to the morphology of the pocket.
This functional profile is achieved through Exur-Teck®, Bioteck®’s patented technology that integrates natural and synthetic components with precision. The result is a biocompatible, homogeneous, and highly stable hydrogel capable of remaining in place for 15–30 days—critical for preventing reinfection and supporting tissue healing.
A biological aid following mechanical treatment
Clinically, H42® is applied after mechanical instrumentation of the pocket, whether through scaling, root planing, or peri-implant decontamination procedures. Once instrumentation is complete:
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The pocket is classified and evaluated.
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Root planing or surface decontamination is performed.
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Subgingival cleaning is carried out.
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A complementary bactericidal treatment may be applied if necessary.
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The site is kept dry.
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The pocket is filled from the bottom up by injecting H42®, allowing the hydrogel to occupy the entire space uniformly.
After application, it is only necessary to keep the area dry for a few moments and continue with routine postoperative instructions. A single application is sufficient to obtain all the benefits of the material.
Properties that deliver superior clinical outcomes
Anatomical adaptation and controlled adhesion
The hydrogel’s consistency and elasticity allow it to adapt seamlessly to the internal geometry of the pocket. This ensures optimal contact with the tissues without causing trauma or compromising the gingival margins.
Effective sealing against bacterial recolonization
Once placed, H42® acts as a physical barrier that prevents bacterial penetration. This long-lasting sealing effect (15–30 days) significantly reduces the risk of reinfection—especially critical in deep or hard-to-access periodontal or peri-implant pockets.
Biocompatibility and physiological support for tissue repair
Collagen, the essential component of the hydrogel, acts as a natural matrix for cell adhesion and proliferation. This supports organised gingival tissue repair and promotes more efficient healing.
Fully resorbable material
No removal is required. The hydrogel degrades naturally without leaving residues, simplifying postoperative care and avoiding additional appointments.
Ease of use and clinical efficiency
H42® requires no refrigeration or special storage conditions. It comes ready to use in a syringe with a male luer-lock connector that ensures a secure fit with a wide range of needles commonly used in dental practice.
Compatible with:
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Gauge 22 to 27 (0.70–0.40 mm)
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Single-orifice, double-lateral, or multi-orifice needles
Its controlled fluidity allows homogeneous extrusion even in narrow or difficult-to-access pockets.
Scientific evidence supporting its effectiveness
In vitro tests show that H42® has high resistance to displacement in a simulated periodontal or peri-implant pocket model. This confirms that the material remains stable in the application site even under mechanical stress.
Additional computational simulations indicate that the extrusion speed remains uniform regardless of the type of needle used. This homogeneous behaviour ensures complete pocket filling, essential for proper sealing.
A comprehensive solution for periodontology and peri-implant therapy
H42® goes beyond the traditional concept of a hydrogel. It is an intelligent biomaterial that combines stability, biological performance, and ease of use to deliver more predictable clinical results. Its ability to seal, protect, and support tissue repair makes it a key resource in the modern treatment of periodontal and peri-implant pockets.
